Reinhard Sterner

University of Regensburg, Institute of Biophysics and Physical Biochemistry, Regensburg, Germany

 

INPEC node since 2004

 

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In the focus of our research are enzymes, which are elaborate proteins that catalyze cellular reactions with high specificity and efficiency. We are using rational design and directed evolution to engineer the stability and catalytic activity of enzymes, to experimentally reconstruct the natural evolution of enzymes, to assign functions to uncharacterized enzymes, to characterize allosteric interactions within multi-enzyme complexes, and to light-regulate enzymatic activity., design

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Keywords: enzyme mechanisms, enzyme engineering, enzyme evolution, enzyme stability, functional annotation of enzymes, light-regulation of enzymes, multi-enzyme complexes